Agnes Jager Selected Research

4-hydroxy-N-desmethyltamoxifen

8/2022	Factors affecting inter-individual variability in endoxifen concentrations in patients with breast cancer: results from the prospective TOTAM trial.
2/2022	Therapeutic Drug Monitoring-Guided Adjuvant Tamoxifen Dosing in Patients with Early Breast Cancer: A Cost-Effectiveness Analysis from the Prospective TOTAM Trial.
1/2022	Influence of probenecid on endoxifen systemic exposure in breast cancer patients on adjuvant tamoxifen treatment.
1/2022	Therapeutic Drug Monitoring of Endoxifen for Tamoxifen Precision Dosing: Feasible in Patients with Hormone-Sensitive Breast Cancer.
2/2021	Correction to: Influence of green tea consumption on endoxifen steady-state concentration in breast cancer patients treated with tamoxifen.
11/2020	Influence of green tea consumption on endoxifen steady-state concentration in breast cancer patients treated with tamoxifen.
3/2019	Impact of Curcumin (with or without Piperine) on the Pharmacokinetics of Tamoxifen.
3/2015	Individualization of tamoxifen therapy: much more than just CYP2D6 genotyping.

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Agnes Jager Research Topics

Disease

86	Breast Neoplasms (Breast Cancer) 11/2022 - 08/2009
50	Neoplasms (Cancer) 11/2022 - 08/2009
8	Neoplasm Metastasis (Metastasis) 11/2022 - 10/2013
5	Circulating Neoplastic Cells 05/2022 - 02/2016
4	Ovarian Neoplasms (Ovarian Cancer) 12/2021 - 08/2012
3	Cardiotoxicity 01/2022 - 08/2020
3	Triple Negative Breast Neoplasms 05/2021 - 02/2013
2	Disease Progression 05/2021 - 02/2016
2	Neutropenia 01/2020 - 04/2015
2	Pain (Aches) 09/2016 - 08/2012
2	Inflammation (Inflammations) 12/2012 - 04/2002
1	Melanoma (Melanoma, Malignant) 03/2022
1	Lung Neoplasms (Lung Cancer) 03/2022
1	Osteonecrosis (Kienbock's Disease) 01/2022
1	Fibrosis (Cirrhosis) 01/2022
1	Fatty Liver 01/2022
1	Dyspepsia (Indigestion) 01/2022
1	Alopecia (Baldness) 08/2021
1	Aneuploidy (Aneuploid) 01/2021
1	Heart Failure 01/2021
1	Hypersensitivity (Allergy) 01/2021
1	Amenorrhea 08/2020
1	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2020
1	Thrombocytopenia (Thrombopenia) 01/2020
1	Genetic Risk Score 01/2020

Drug/Important Bio-Agent (IBA)

18	Estrogen ReceptorsIBA 11/2022 - 10/2010
11	Tamoxifen FDA LinkGeneric 02/2022 - 06/2013
11	Hormones (Hormone)IBA 01/2022 - 10/2010
10	Pharmaceutical PreparationsIBA 03/2022 - 01/2015
10	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 12/2018
9	Biomarkers (Surrogate Marker)IBA 06/2022 - 03/2015
8	4-hydroxy-N-desmethyltamoxifenIBA 08/2022 - 03/2015
7	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 09/2014
7	Cell-Free Nucleic AcidsIBA 04/2021 - 01/2017
6	AnthracyclinesIBA 01/2021 - 08/2009
5	Trastuzumab (Herceptin)FDA Link 01/2022 - 10/2016
5	Paclitaxel (Taxol)FDA LinkGeneric 08/2021 - 10/2016
5	Progesterone Receptors (Progesterone Receptor)IBA 05/2021 - 02/2011
4	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2022 - 09/2014
3	MicroRNAs (MicroRNA)IBA 12/2021 - 01/2014
3	human ERBB2 proteinIBA 08/2020 - 10/2016
3	Carboplatin (JM8)FDA LinkGeneric 01/2020 - 09/2019
3	Aromatase InhibitorsIBA 01/2020 - 02/2016
3	Phenobarbital (Luminal)FDA Link 01/2020 - 08/2011
3	Proteins (Proteins, Gene)FDA Link 04/2016 - 09/2014
2	Estradiol (Delestrogen)FDA LinkGeneric 11/2022 - 11/2020
2	Circulating Tumor DNAIBA 05/2022 - 01/2021
2	Estrogens (Estrogen)FDA Link 01/2022 - 05/2021
2	Diphosphonates (Bisphosphonates)IBA 01/2022 - 09/2016
2	Biological ProductsIBA 04/2021 - 08/2011
2	TeaIBA 02/2021 - 11/2020
2	Capsules (Microcapsules)IBA 01/2020 - 01/2020
2	olaparibIBA 01/2020 - 01/2020
2	Indicators and Reagents (Reagents)IBA 01/2020 - 01/2020
2	Messenger RNA (mRNA)IBA 01/2019 - 02/2016
2	taxaneIBA 02/2018 - 02/2012
2	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2017 - 02/2016
2	Bevacizumab (Avastin)FDA Link 10/2016 - 04/2016
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 02/2016 - 04/2015
2	Paroxetine (Paxil)FDA LinkGeneric 02/2016 - 06/2013
2	Fluoxetine (Prozac)FDA LinkGeneric 02/2016 - 06/2013
2	Antidepressive Agents (Antidepressants)IBA 02/2016 - 06/2013
1	16-fluoroestradiolIBA 11/2022
1	Cytostatic AgentsIBA 02/2022
1	Probenecid (Benemid)FDA LinkGeneric 01/2022
1	Ibandronic Acid (Boniva)FDA Link 01/2022
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2022
1	LipidsIBA 01/2022
1	Progestins (Progestagens)IBA 05/2021
1	ribociclibIBA 02/2021
1	abemaciclibIBA 02/2021
1	palbociclibIBA 02/2021
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2021
1	Oral ContraceptivesIBA 01/2021
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2021
1	N 30IBA 01/2021
1	Ranitidine (Zantac)FDA LinkGeneric 01/2021
1	ElementsIBA 01/2021
1	Progesterone FDA LinkGeneric 01/2021
1	elacestrantIBA 11/2020
1	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 11/2020
1	NucleotidesIBA 02/2020
1	TabletsIBA 01/2020
1	Everolimus FDA Link 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	exemestane (Aromasin)FDA Link 01/2020
1	Epidermal Growth Factor (EGF)IBA 10/2019
1	Acetic Acid (Vinegar)FDA LinkGeneric 10/2019
1	formic acid (formate)IBA 10/2019
1	Edetic Acid (EDTA)FDA Link 10/2019
1	Gemcitabine FDA Link 09/2019
1	iniparibIBA 09/2019

Therapy/Procedure

24	Drug Therapy (Chemotherapy) 07/2022 - 08/2009
22	Therapeutics 03/2022 - 02/2012
7	Adjuvant Chemotherapy 01/2020 - 10/2009
6	Radiotherapy 01/2020 - 02/2015
5	Segmental Mastectomy (Lumpectomy) 01/2020 - 02/2015
4	Mastectomy (Mammectomy) 12/2019 - 02/2015
2	Hormone Replacement Therapy (Therapy, Hormone Replacement) 05/2021 - 08/2020
2	Adjuvant Radiotherapy 11/2015 - 02/2015